Microvenular hemangioma is a rare, slowly growing, benign vascular tumor. It usually presents as a solitary, asymptomatic, purple to red papule or plaque in young to middle-aged adults. Histologically, the tumor is composed of irregular, branching venules with inconspicuous lumina with a lack of endothelial atypia. We describe a case of microvenular hemangioma in a year-old female. The lesion was slightly tender unlike that of previously reported cases. In the context of the histological similarity to a low-grade malignant tumor, Kaposi's sarcoma, the awareness of microvenular hemangioma, a benign vascular tumor, is important.
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Background: Microvenular hemangioma is an uncommon benign vascular tumor that can potentially be mistaken for malignancy. Methods: We reviewed the histopathologic and clinical features of 13 microvenular hemangiomas, which represents the largest series reported to date.
All presented with a similar history of a new, asymptomatic, stable or slow-growing, red to purple plaque or nodule. The lesions were located on the extremities, chest, back or abdomen. Two patients had multiple lesions. In six, a vascular tumor was not suspected clinically. Histologically, all were composed of a dermal proliferation of thin-walled, often branching, vascular channels dissecting through collagen fibers.
The vessels were surrounded by a conspicuous layer of pericytes. Immunohistochemistry showed that all were positive for a vascular marker. Stains for WT-1 were positive in 9 of Follow-up available on six patients showed no recurrences.
Conclusion: The histomorphology of microvenular hemangioma frequently raises concern for a malignant vascular lesion, especially Kaposi sarcoma. Identification of characteristic features, particularly the pericyte layer in routinely stained sections or with an SMA immunostain, allows an accurate diagnosis.
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Similar articles Eruptive microvenular hemangiomas in 4 Chinese patients: clinicopathologic correlation and review of the literature. Xu XL, et al. Am J Dermatopathol. PMID: Review. Microvenular hemangioma. Kim YC, et al.
PMID: Microvenular hemangioma presenting with numerous bilateral macules, patches, and plaques: a case report and review of the literature. Linos K, et al. Aloi F, et al. Jouary T, et al. Ann Dermatol Venereol. PMID: French. Show more similar articles See all similar articles. Cited by 2 articles Immunoreactivity of Wilms tumor 1 WT1 as an additional evidence supporting hemangiomatous rather than inflammatory origin in the etiopathogenesis of angiolymphoid hyperplasia with eosinophilia.
Tokat F, et al. Dermatol Pract Concept. An unusual lesion on the nose: microvenular hemangioma. Mansur AT, et al. MeSH terms Adult Actions. Aged Actions. Child, Preschool Actions. Female Actions. Humans Actions. Immunohistochemistry Actions. Male Actions. Middle Aged Actions. Full-text links [x] Wiley. Copy Download.
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Microvenular hemangioma MH is an acquired benign vascular tumor, occurring on the trunk and limbs in young to middle-aged adults without any gender predilection. MH was first described by Bantel et al in 1. The etiology of MH is unknown. Even in these reported cases, accounts of multiple MH are extremely uncommon. The present study reports a case of multiple MH.