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Clinical characteristics of the acute phase of feline immunodeficiency virus experimental infection. Marcelo S. Froes II ; Adriana L. Hagiwara IV. As a result of FIV infection of cats, feline immunodeficiency syndrome might be seen in the latter phase of infection. Gengivitis, weight loss, spread enlargement lymph nodes, anemia, chronic renal failure, neurological disturbances, chronic diarrhea, and oportunistic bacterial infections are commonly found.

The acute phase of the infection might be unnoticed, making the diagnosis difficult and delaying the adoption of profilatic measures, in order to reduce FIV transmission for other susceptible cats.

Aiming to study the clinical characteristics of the acute phase of FIV infection, ten young eight month old cats mixed breed were succesfully inoculated by intravenous route with one mL of blood obtained from one FIV-B positive cat. CBC counting, abdominal ultrasonography and ophtalmologic exams were done weekly, fortnightly and monthly during twelve weeks p. Mild tendency to lymphopenia at second week and neutropenia between fifth and seventh weeks p.

The latters became evident starting on fourth week and remained throughout the twelve weeks observation period. Only one cat showed unilateral rigt uveitis. The acute phase of FIV infection elapsed with inespecific clinical manifestations. Lymph node, hepatic and spleen enlargements seen, though, suggest the needs for indication of tests for the diagnosis of FIV infection in all cats presenting those signs, thus allowing early diagnosis of FIV infection and the adoption of prophylatic measures.

Index terms: Feline, virus, feline immunodeficiency, acute infection, ultrasonography. Pedersen et al. A fase aguda pode passar despercebida na maioria dos gatos. Eventualmente pode ocorrer neutropenia Sparkes et al. Segundo Callanan et al. De acordo com Rimmelzwaan et al. Brown et al. Em um estudo publicado por Hanson et al. De acordo com English et al. Beebe A. Primary stage of feline immunodeficiency virus infection: Viral dissemination and cellular targets.

Brown P. Pathological features of lymphoid tissues in cats with natural feline immunodeficiency virus infection. Burkhard M. Kinetics of early FIV infection in cats exposed via the vaginal versus intravenous route. Callanan J. Morphologic characterization of the lymph node changes in feline immunodeficiency virus infection as an animal model of AIDS, p.

In: Racz P. Karger, Basel. Dean G. Proviral burden and infection kinetics of feline imunodeficiency virus in lymphocyte subsets of blood and lymph node. Virology Diehl L. Induction of accelerated feline immunodeficiency virus disease by acute-phase virus passage. Dow S. In vivo monocyte tropism of pathogenic feline immunodeficiency viruses. English R. Development of clinical disease in cats experimentally infected with feline immunodeficiency virus.

Intraocular disease associated with feline immuno-deficiency virus infection in cats. Hanson J. Ultrasonographic appearance of splenic disease in cats. Ultrasound Hohdatsu T.

Genetic subtyping and epidemiological study of feline immuno-deficiency virus by nested polymerase chain reaction-restriction fragment length polymorphism analysis of the gag gene.

Methods Lara V. Levy J. Sero-prevalence of feline leukemia virus and feline immunodeficiency virus infection among cats in North America and risk factors for sero-positivity. Linenberger M. Marrow acessory cell infection and alterations in hematopoiesis accompany severe neutropenia during experimental acute infections with feline immunodeficiency virus.

Blood The effects of feline retroviruses on cytokine expression. Loesenbeck G. Findings in the eyes of serologically FIV feline immunodeficiency virus positive cats.

Matsumura S. Pathologic features of acquired immunodeficiency-like syndrome in cats experimentally infected with feline immuno-deficiency virus. Moraillon A. In vitro properties and experimental pathogenic effect of three strains of feline immunodeficiency viruses FIV isolated from cats with terminal disease.

Nasisse M. Clinical and laboratory findings in chronic conjunctivitis in cats: 91 cases Phillips T. Neurology Pedersen N. Isolation of a T-lymphotropic virus from domestic cats with an immunodeficiency-like syndrome. Science Reche Jr A. Rimmelzwaan G. Gag- and env-specific serum antibodies in cats after natural and experimental infection with feline immunodeficiency virus. Sellon R. Feline immunodeficiency virus infection, p.

In: Greene C. Saunders Elsevier, St Louis. Souza H. Sparkes A. Feline immunodeficiency virus infection: Clinico-pathologic findings in 90 naturally occuring cases. Tompkins M. Lentivirus-induced immune dysregulation. Torten M. Progressive immune dysfunction in cats experimentally infected with feline immunodeficiency virus. Troth S. In vivo CXCR4 expression, lymphoid cell phenotype, and feline immunodeficiency virus infection. Willis A. Feline leukemia virus and feline immundeficiency virus. North Am.

Recebido em 11 de maio de All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Services on Demand Journal. How to cite this article.


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