Please call the pharmacy to inquire about store hours or delivery service as they may have changed. This medication contains an antibiotic. Typically, it is used to treat infections. It requires several days to take effect. This drug can, on occasion, be administered in a hospital or clinic setting by a doctor or a nurse, but can also be used at home.
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Among the new antibiotics investigated clinically in Houston during the past two years, colistin Coly-Mycin has been one of the most promising. This antibiotic was isolated in Japan by Yosuo Koyama in from culture filtrates of Bacillus colistinus, a bacterium closely related to Bacillus polymyxa, the source of the polymyxins.
Its pharmacology has been studied in Japan, Italy, France, and, more recently, this country. A summary of the findings of these studies indicates that the chemical, pharmacological, and antimicrobial activity of colistin is closely related to the polymyxins, Clinically, however, colistin causes fewer undesirable side-effects. Colistin is a complex polypeptide, with an empirical formula of C 45 H 85 O 10 N 13 and a molecular weight of Its acid salts are stable in solution even for very long periods; alkaline salts are less stable.
It is available as colistin sulfate for oral and ophthalmic use, and as. Arch Intern Med. Coronavirus Resource Center. All Rights Reserved. Twitter Facebook Email.
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Coly Mycin M
Medically reviewed by Drugs. Last updated on Mar 23, Antibacterial; prodrug of colistin a polymyxin antibiotic structurally and pharmacologically related to polymyxin B. Treatment of acute or chronic infections caused by certain susceptible gram-negative bacteria e.