ESTRUCTURA DEL SARCOMERO PDF

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Show More. Be the first to like this. No Downloads. Views Total views. Actions Shares. Embeds 0 No embeds. No notes for slide. The drawings at right show these muscles in cross section. Skeletal muscle is composed of large, elongated, multinucleated fibers. Cardiac muscle is composed of irregular branched cells bound together longitudinally by intercalated disks.

Smooth muscle is an agglomerate of fusiform cells. The density of the packing between the cells depends on the amount of extracellular connective tissue present. Skeletal Muscle Cells Skeletal muscle cells are long up to 30 cm , possess a diameter of m, and are multinucleated as a result of myoblast fusion Nuclei are found just below the sarcolemma Each muscle fiber is inervated by a motor nerve 1 2.

Goldspink J Anat Filamentos gruesos y finos 3 4. Miosina es un motor molecular Myosin is a hexamer: 2 myosin heavy chains 4 myosin light chains Cabeza de miosina: retiene todas las funciones de motor de la miosina, es decir, la abilidad de producir fuerza y movimiento. Troponina C y calcio Tropomiosina Gordon et al. The metabolic response to exercise is similar to the fasting response because similar fuels must be mobilized and generated for oxidation. If exercise continues, the stores may be depleted.

The accumulation of lactic acid in muscle and circulation is a limiting factor for glycolysis, not the depletion of muscle glycogen. After several minutes of exhaustive anerobic exercise, one incurs an oxygen debt of up to 12 L.

From 6 to 8 L are required to resynthesize the lactic acid to glucose or oxidize it to CO2. About 2 L are required for normal replenishment of muscle ATP and creatine phosphate. About 2 L more are needed to replenish the oxygen normally found in the lungs and body fluids bound to hemoglobin or myoglobin. Glucose substrates from the circulation are added to muscle glycogen and there is a manyfold increase in glucose uptake from the plasma by some groups of muscles.

Glycogenolysis takes place to offset this glucose drain. As glycogen stores become exhausted by continued exercise, gluconeogenesis takes place from amino acids released by muscle proteolysis. Finally, free fatty acids are liberated from adipose tissue. In time, these free fatty acids will supply two thirds of the energy needed to maintain the exercise.

After the termination of exercise, energy is needed to rebuild the glycogen stores in the liver and muscle. You just clipped your first slide! Clipping is a handy way to collect important slides you want to go back to later. Now customize the name of a clipboard to store your clips. Visibility Others can see my Clipboard.

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INON Z240 USER MANUAL PDF

File:Sarcomere esp.png

Knowing the ultrastructure of skeletal muscle is critical to understand how it works under normal situation and the disorders caused by extreme or pathological conditions. Sarcomere is the basic structural unit of striated muscle tissue. An important element of sarcomere architecture are the intermediate filaments, including the desmin protein. Desmin protein contributes to maintenance of cell integrity, efficient transmission of force and mechanochemical signaling within the myocyte. Because of this, desmin protein has constantly been a focus of research that investigates its alterations associated to damage and muscle atrophy under different conditions. The purpose of the following literature review is to describe the basic concepts of muscle ultrastructure, emphasizing the desmin protein role under conditions of muscle disuse atrophy and aging.

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DIE ETHNISCHE SUBERUNG PALSTINAS PDF

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