Thirty-one horses with naturally occurring summer sores were given a single IM injection of 0. The typical summer sore was replaced by healthy pink granulation tissue at 7 days and this healed after 1 to 5 weeks. Five of the 31 infected horses did not respond to a single dose and appeared to have become reinfected. Biopsy samples taken from 3 of these horses were positive for larvae 2 to 4 weeks after the 1st dose, but became negative and healed 1 to 2 weeks after a 2nd dose with ivermectin. Histopathologic examination of sections from lesions before anthelmintic treatment showed granulation tissue with marked eosinophilic infiltration, multiple eosinophilic abscesses, and transverse sections of nematodes.
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Lyons ET, et al. Am J Vet Res. A xenodiagnostic method using Musca domestica for the diagnosis of gastric habronemosis and examining the anthelmintic efficacy of moxidectin. Schuster RK, Sivakumar S. Schuster RK, et al. Vet Parasitol. Epub Jun Ivermectin as an antiparasitic agent in horses. J S Afr Vet Assoc. PMID: Review. Hasslinger MA. Tierarztl Prax.
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Parasitol Res. Epub Nov 5. The comparative morphology of three equine habronematid nematodes: SEM observations. Naem S. Epub Jul 4. Epub May MeSH terms Animals Actions. Horses Actions. Full-text links [x] Wiley. Copy Download.
Efficacy of Ivermectin Against Cutaneous Draschia and Habronema Infection (Summer Sores) in Horses
Equine stomach worms, Habronema muscae , H microstoma , and Draschia megastoma , infect the mucosal lining of the stomach and cause catarrhal gastritis. Draschia can cause tumor-like swellings along the margo plicatus, but this parasite has become rare in domestic horses. In their gastric stage, Habronema parasites rarely cause clinical problems, and their most significant manifestation is the cutaneous condition often referred to as summer sores. Anthelmintic efficacy has not been recently evaluated against these parasites, but macrocyclic lactones are still believed to be effective against the gastric stages. Habronema and Draschia spp are vector-borne parasites using muscid flies as intermediate hosts. The adult parasites establish in the stomach upon ingestion of larvae deposited by flies around the mouth or by ingestion of dead flies carrying the larvae. Within the stomach, parasites become adults in about 8 weeks.